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In my new Iphone 4s left bottom speaker isn't working and also the right side of my headphones isn't working, can anyone help?
There is not a speaker on the left, that's the microphone.
As for the headset, have you tried a different headset?
Have you possibly enabled Mono audio? Settings > General > Accessibility > Mono Audio
Yes mono audio is enabled.
No i haven't tried with other headset.
Will other brand headphones work in iphone?
Disable mono audio. Mono should be used if you only want to hear in one ear piece (like a bluetooth earpiece.) Even then it's not necessary.
Any stereo headset will work with an iPhone.

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